Research

Research Capabilities:

• Pharmaceutics Department

  • Expertise in the Development of NDDS (SLN & NLC)
  • Expertise in Tablet Granulation and Coating
  • Lipid drug delivery Technology
  • Engineering cellular based carrier
  • Expertise in solubilisation techniques
  • Design and optimization of orodispersible dosage forms
  • Solid dispersion,
  • Solid solution,
  • Nano-crystals,
  • Nano-emulsions
  • Drug-polymer conjugates
  • Microsphere Drug Delivery
  • Advanced characterisation techniques like Raman spectroscopy, Raman imaging, 2D NMR and Atomic force microscopy of solid formulations
  • Generic ANDA Development of Dosage forms including Paragraph (IV) projects.
  • In Vitro Permeability studies with Porcine and Goat Buccal Mucosa for study of Drug Diffusion.
  • Solubility enhancement of poorly soluble drug
  • Bioavailability Enhancement of class IV molecules
  • Design and development of nano emulsion
  • Design and development of lipid based drug delivery systems
  • Orodispersible formulations
  • Mouth Dissolving Films-Development and evaluation(Provisional Patent Field)
  • Orodental and mucoadhesive film-Design Development and evaluation
  • Liquid filled hard gelatin capsules
  • SMEDDS for colon targeting
  • Development of gel and transdermal preparations for allergy burn and wounds
  • Evaluation of mouth sprays
  • Development of nutraceutical product
  • Design and development of generic product for US market with QbD approach.
  • In-vitro model for permeability studies
  • Continuous HME processing and Process Analytical Tools (PAT).

  

• Pharmaceutical Chemistry and Analysis Departments

  • Molecular modelling
  • Target-based designing of novel therapeutic agents
  • Ligand – based (pharmacophore, SAR, QSAR) drug designing
  • In silico ‘mechanism of action’ studies
  • In silico ‘knock-out’ / mutation’ studies
  • In-silico identification of protein target hotspots
  • Lead optimisation
  • Drug repurposing
  • Synthesis of drugs by
  • Conventional method
  • Solvent-less approach
  • Microwave-assisted methods
  • Multicomponent / Convergent methods
  • Analytical method development and validation of drugs
  • Structure elucidation by FTIR, Mass, NMR
  • Study of characteristics of drug through FTIR
  

• Pharmacology Department

  • Toxicities Studies (acute, sub-acute & chronic toxicity studies)
  • Antimicrobial, Antifungal studies
  • Expertise in development of animal models for
  • Diabetes
  • Burns
  • Anti-inflammatory research
  • Anti-obesity activity for diet-induced model (High fat diet).
  • Pharmacokinetic /pharmacodynamics studies.
  • Expertise in developing assays using various animal tissues like heart and abdominal muscle preparation.

  

• Pharmacognosy Department

  • Design and development of herbal preparations
  • Phytochemical evaluation of various natural products
  • Standardization of herbal drugs
  • Optimization of extraction of herbal drugs and isolation of active constituents
  • HPTLC method development and validation for herbal extracts/formulations
  • Development and validation of GC method
  • Development and standardisation of herbal formulation /nutraceuticals/ cosmeceuticals
  • Biological screening of herbal drugs/formulations
  • Optimising solubility of natural products